Protein-protein Interactions

Doctor Thomas Nuhse describes the process by which proteins interact and work together to produce an outcome.

Many proteins only work together with other proteins. The reason for that is, for example, to regulate the activity of one protein. One protein might be an enzyme - it might cleave something in two or add, for example, a phosphate to another protein if it is a kinase. Quite often the kinase doesn’t know when and where it should be active - where it should sit in the cell, which other proteins it should add that phosphate onto. And quite often then kinases work together with other proteins in what we call a protein-protein interaction to specify where the activity of the first protein should happen.